In food industry, there are various types of preservatives, and their antibacterial mechanisms and spectra are different. A single preservative usually only inhibit a specific spoilage bacterium, and has no or weak inhibitory effect on other bacteria. At the same time, it is also easy for microorganisms to develop adaptability. Based on fence technology, different types of preservatives can be used in combination, and their synergistic effect can not only enhance the antibacterial effect, but also reduce the amount of single preservatives used.
Natamycin is a polyene macrolide antibacterial agent mainly fermented by Streptomyces such as Streptomyces natalis and Streptomyces botrytis; It usually exists in an enol structure and is a odorless and tasteless crystalline powder. Natamycin can effectively inhibit yeast and mold, suppress food spoilage, and prevent damage caused by fungal toxins to the human body.
It is a specific and highly effective antifungal agent that has a good inhibitory effect on almost all yeasts and molds. The minimum inhibitory concentration of Natamycin against Aspergillus is 0.63mg/kg, against Aspergillus niger is 1.80mg/kg, and against Penicillium islandium is 1.10mg/kg. For fungi in gernal, the minimum inhibitory concentration is approximately 1mg/L.
Nisin is a peptide substance with bactericidal effect produced by Streptococcus lactiae during metabolism. It consists of 34 amino acid residues and is a highly efficient and non-toxic natural preservative. The antibacterial spectrum of Nisin is narrow and can only effectively inhibit food spoilage caused by bacteria.
It has a good antibacterial effect on most Gram-positive bacteria, especially on Staphylococcus aureus and Bacillus subtilis. It can act on bacterial cell membranes, form pore like structures, disrupt the balance between inside and outside the cell, and lead to cell death; It can also inhibit the synthesis of peptidoglycans, blocking cell wall synthesis and thus inhibiting cell growth.
Therefore, the combination of Natamycin and Nisn can simultaneously inhibit the growth of fungi and bacteria, extending the shelf life of food. In recent years, relevant research has proven the above idea in practice.
Jiangsu Zipin Biotech will introduce premium compound preservative products with a focus on customer and market demands.
